Turkesterone

Turkesterone is an ecdysteroid derivative found in numerous plant species, including Ajuga turkestanica. Most of the data for its anabolic activity is from the 70s and probably the best research comes from a Russian paper that compared the anabolic activity of turkesterone and the anabolic steroid d-bol. Activity was reported to be similar(in mice). The paper I posted proposes a mechanism for how turkesterone and other ecdysteroids work. The anabolic activity is based on the position of the hydroxyl groups(OH) on the molecule, as well as the conjugated C=O and C=C bond that is present in testosterone(see pic). The OH on carbon 11 is very important to its high anabolic activity, as well. If you scroll, you’ll see its binding affinity for the androgen receptor high, although it can bind to the estrogen and glucocorticoid receptors, too. There isn’t a lot of human data for turkesterone, but it does seem to have anabolic effects. Bioavailability is poor, so if you’re taking an extract of plant material containing turkesterone, you may need to take 2000mg a day, split up into doses. If you have taken turkesterone before, comment below