Are there specific pathways in the body that are activated by Sildamax 100 Mg to

Sildamax 100 mg contains sildenafil citrate, which belongs to a class of medications called phosphodiesterase type 5 (PDE5) inhibitors. These inhibitors work by blocking the action of the enzyme phosphodiesterase type 5, which is responsible for breaking down cyclic guanosine monophosphate (cGMP) in the smooth muscle cells of the penis. During sexual stimulation, the release of nitric oxide (NO) in the corpus cavernosum of the penis leads to the activation of guanylate cyclase, an enzyme that increases levels of cGMP. This, in turn, relaxes the smooth muscle cells and increases blood flow into the penile tissues, resulting in an erection. However, PDE5 enzyme breaks down cGMP, thereby reducing its levels and causing the smooth muscle cells to contract, leading to a decrease in blood flow and loss of erection. By inhibiting PDE5, medications like Sildamax 100mg prevent the degradation of cGMP, allowing it to accumulate and maintain the relaxation of smooth muscle cells, thereby facilitating and sustaining erections. So, the primary pathway activated by Sildamax 100 mg involves the inhibition of PDE5, leading to increased levels of cGMP, relaxation of smooth muscle cells in the penis, and enhanced blood flow, ultimately resulting in improved erectile function.