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Zillagreybeard 3 years, 7 months ago.
How Body Fat (specifically) regulates our metabolism
Discussion in 'Nutrition and Supplements' started by Zillagreybeard, Mar 11, 2022.You must be logged in to reply to this topic.
DeusChem replied 4 months, 3 weeks ago
Kristenmitchell replied 4 months, 3 weeks ago
DominicThomas replied 5 months, 1 week ago
How Body Fat (specifically) regulates our metabolism ⭕️
In a new study conducted by A. Martin & colleagues, the goal was to characterize the contribution of the loss of “energy-expending” tissues and metabolic adaptations to the reduction in RMR, following weight loss.
Interestingly enough, RMR was reduced by ~101 kcal/d as participants lost ~7kg. On average, 60% of the reduction in RMR were explained by energy-expending tissues losses, while 40% were attributed to metabolic adaptations.
The loss of skeletal muscle was not significantly related to the reduction in RMR, whereas adipose tissue losses were positively associated with it.
Metabolic adaptations were correlated with declines in Leptin, Triiodothyronine (T3), and Insulin.
Should I get deeper, with more posts on the topic of metabolic adaptations ? Let me know with a comment down below!
Reference:
Martin A, Fox D, Murphy CA, Hofmann H, Koehler K. Tissue losses and metabolic adaptations both contribute to the reduction in resting metabolic rate following weight loss. Int J Obes (Lond). 2022 Feb 18. doi: 10.1038/s41366-022-01090-7. Epub ahead of print. PMID: 35181758.